Chronic kidney disease (CKD) may affect excretion and metabolism of vitamins, but data for dogs are limited. In this study, blood vitamin levels were investigated in 19 dogs with chronic renal failure. High performance liquid chromatography was used to quantify retinol, retinyl esters, tocopherol, thiamine, riboflavin, pyridoxal-5′-phosphate, ascorbic acid and 25-hydroxycholecalciferol concentrations, whereas cobalamin, folate, biotin and pantothenic acid were measured by microbiological methods.
Levels of retinol, retinyl palmitate, ascorbic acid and vitamins B1, B2 and B6 were increased compared to healthy dogs. Dogs with CKD showed decreased concentrations of 25-hydroxycholecalciferol and folate. Alpha-tocopherol, biotin, pantothenate and cobalamin levels were not significantly different between controls and dogs with CKD.
Whether lower vitamin D and folate concentrations in dogs with CKD justify supplementation has to be evaluated in future studies.
Source: A. Gallera et al., 2012. Blood vitamin levels in dogs with chronic kidney disease. Vet J 192: 226–231. doi: 10.1016/j.tvjl.2011.06.026
We asked Carol Jones-Adams, who founded and runs functional treat maker Overby Farm with her husband and business partner, Bob Adams, to tell us more about her company
The company builds on its boutique business with three new lines for pet stores, including baked dog food and treats
Is the Proportions whole food nutrition program a healthier alternative to conventional diets?
The lowly pea appears to be an effective ingredient for the next generation of dog and cat diets
Tomato pomace has the potential to provide additional nutrition and health benefits
With the availability of quality ingredients declining, perhaps we need to explore this category
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