objective of this study was to determine associations between serum
concentrations of omega-3 polyunsaturated fatty acids or body condition and
serum concentrations of adipokines in healthy dogs. Body condition score and
percentage of body fat were determined for 62 adult, client-owned dogs. Serum
was harvested for total lipid determination, fatty acid analysis and concentrations
of adiponectin, leptin, insulin, glucose and triglyceride. We also determined associations
between those concentrations and each of several variables (age, sex,
percentage of body fat and concentrations of total lipid, α-linolenic acid,
eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid).
concentrations of docosapentaenoic acid were significantly, positively
associated with adiponectin and leptin and negatively associated with triglyceride.
Concentrations of α-linolenic acid were significantly, positively associated
with triglyceride. No significant associations were detected between serum
concentrations of eicosapentaenoic acid or docosahexaenoic acid and any of the
of body fat was significantly, positively associated with concentrations of
leptin, insulin and triglyceride but not with adiponectin. Age was positively
associated with leptin, insulin and triglyceride and negatively associated with
adiponectin. Sex did not significantly affect concentrations for any of the
acid may increase serum concentrations of adiponectin and leptin and decrease
triglyceride concentration in healthy dogs.
Source: M. Mazaki-Tovi
et al., 2012. Effect of omega-3
polyunsaturated fatty acids and body condition on serum concentrations of adipokines
in healthy dogs. AJVR 73: 1273-1281. doi:
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