It's the "Intel inside" kind of molecule that allows others to function to their full potential.
Dogs and cats, like many other species, require choline.
It's the "Intel inside" kind of molecule that allows others to
function to their full potential. Almost all commercial
petfoods contain supplemental choline, predominantly from
choline chloride. However, putting choline chloride into the
formula can have profound effects on the way the ingredients
are combined and processed during production due to the
molecule's hygroscopic (water-loving) nature.
Studies with dogs in the 1930s first led researchers to
identify choline as a necessary nutrient. Since that time it
has been recognized as a:
Key component of cell membrane
Vital part of the neurotransmitter
Lipotropic agent in fat utilization
and lipid signaling; and
Methyl group donor in reactions
involving methionine, folic acid, vitamin B12, glycine and
The choline oxidation product betaine also acts as an
osmolyte in the kidney. In its absence, choline deficiency can
result and cause weight loss, vomiting, fatty liver and even
death in dogs and cats.While often grouped with theB-vitamins, choline is actually
a closer fit, structurally and functionally, with the amino
acids and fatty acids. Its similarity to B-vitamins is
associated with the way it moves through the body.
Specifically, choline is soluble in polar solvents like water
and alcohol, has no bodily storage depots and is metabolized
and excreted in proportion to the amount consumed. Thus, it
must be replenished daily. Because of this constant efflux ...