study investigated the influence of dietary supplementation with L-carnitine on
metabolic rate, fatty acid oxidation, weight loss and lean body mass (LBM) in
overweight cats undergoing rapid weight reduction. Thirty-two healthy, neutered,
colony-housed cats were fed an energy-dense diet unrestricted for six months,
then randomly assigned to four groups and fed a weight-reduction diet supplemented
with 0 (control), 50, 100 or 150 μg of carnitine/g of diet. Following weight
loss, cats were allowed unrestricted feeding of the energy-dense diet to
investigate weight gain after test diet cessation.
weekly weight loss in all groups was 1.3%, with no difference among groups in
overall or cumulative percentage weight loss. During restricted feeding, the
resting energy expenditure-to-LBM ratio was significantly higher in cats that
received L-carnitine than in those that ate the control diet. Respiratory
quotient was significantly lower in cats that received L-carnitine on day 42,
compared with pre-diet, and in all cats that received L-carnitine compared with
the control group.
significant increase in palmitate flux rate in cats fed the diet with 150 μg of
carnitine/g relative to the control group on day 42 corresponded to
significantly increased stoichiometric fat oxidation in the L-carnitine group
(over 62% vs. 14% for the control group). Weight gain (as high as 28%) was
evident within 35 days after unrestricted feeding was reintroduced.
L-carnitine supplementation appeared to have a metabolic effect in overweight
cats undergoing rapid weight loss that facilitated fatty acid oxidation.
Source: S.A. Center et al., 2012. Influence of dietary
supplementation with L-carnitine on metabolic rate, fatty acid oxidation, body
condition and weight loss in overweight cats. AJVR 73: 1002-1015. doi: 10.2460/ajvr.73.7.1002
5 small steps would streamline information on petfood ingredients to help communicate with pet owners
The lowly pea appears to be an effective ingredient for the next generation of dog and cat diets
Tomato pomace has the potential to provide additional nutrition and health benefits
It's an "Intel inside" type of molecule -- but also a problem child
The question is whether they provide additional benefit to the dog or cat
What is this quiet, unassuming ingredient, and should it be there?
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