Advertisement

Pet Food Safety
On June 20, 2012

Aflatoxicosis from commercial diet in 50 dogs

The mortality rate was 68%, suggesting that dogs with aflatoxicosis have poor prognosis.

Aflatoxins, produced by Aspergillus spp., are toxic contaminants of stored grain. This study describes 50 dogs presented with foodborne aflatoxicosis.

Common clinical signs included lethargy (78%), vomiting (76%), anorexia (74%), icterus (66%), depression (66%), melena (60%), haematuria (36%) and diarrhea (36%). Common laboratory abnormalities included increased activities of aspartate aminotransferase (86%), alkaline phosphatase (84%) and alanine aminotransferase (79%), hypoantithrombinaemia (86%), prolonged prothrombin (PT, 82%) and activated partial thromboplastin times (aPTT, 80%), hyperbilirubinaemia (73%), hypocholesterolaemia (60%) hypoalbuminemia (47%) and thrombocytopenia (42%).

Non-survivors had longer PT and aPTT and lower antithrombin at presentation compared to survivors. Hyperbilirubinaemia (>56.6 μmol/L) and albumin concentration <32.5 g/L at presentation were risk factors for mortality. Common complications included disseminated intravascular coagulation (58%), hepatic encephalopathy (35%) and acute kidney injury (4%). The mortality rate was 68%, suggesting that dogs with aflatoxicosis have poor prognosis.

Source : Y. Bruchim et al., 2012. Accidental fatal aflatoxicosis due to contaminated commercial diet in 50 dogs. Res Vet Sci 93: 279-287. doi: 10.1016/j.rvsc.2011.07.024

Comments powered by Disqus

Advertisement

Petfood Forum China

Advertisement

Advertisement

Read the June issue of Petfood Industry!

June 2015

The June 2015 issue of Petfood Industry profiles the family owned company, CANIDAE, and how it has succeeded in carving a niche in the pet specialty market. The company believes educating retailers about its products and focusing on consumers' needs are keys to maintaining their spot in the market. Plus, learn how pet food manufacturers can use their product’s packaging as a way of branding to attract customers and why companies are eyeing Poland for market expansion opportunities.

READ MORE in Petfood Industry magazine

Advertisement