This study aimed to determine the effects of supplemental vitamin E and/or selenium on selected parameters of the immune system of the cat.
Nine diets were fed in a 3â€‰Ã—â€‰3 factorial design with no supplementation (control) and either moderate or high levels of vitamin E and/or selenium added to a complete and balanced basal diet. After 28 days of feeding, enhanced lymphocyte proliferative responses to Concanavalin A and phytohaemagglutinin were observed in cats fed diets containing supplemental vitamin E, irrespective of whether they also contained selenium. Cats in the medium vitamin E, high vitamin E, medium vitamin Eâ€‰+â€‰medium selenium, high vitamin Eâ€‰+â€‰medium selenium, and high vitamin Eâ€‰+â€‰high selenium groups all showed enhancement of phagocytic activity compared to control animals.
Results indicate that a supplemental level of 225â€‰mg/kg dietetic management diet of vitamin E appears to have beneficial effects on immune function in the cat.
Source: Teresa O’Brien et al., 2015. Moderate dietary supplementation with vitamin E enhances lymphocyte functionality in the adult cat. Res Vet Scionline, January 2015. doi:10.1016/j.rvsc.2015.01.007.