The FDA has issued a final document, "Small Entities Compliance Guide for Renderers - Substances Prohibited from use in Animal Food or Feed," to provide guidance on the requirements of the  final rule , according to an  update  from the administration's  Center for Veterinary Medicine .

This rule is in an effort to protect consumers against  bovine spongiform encephalopathy , otherwise known as "mad cow disease."

The guidance's purpose is to help rendering firms comply with the rule that became effective April 27 of this year. The guidance should also help slaughter facilities and farms supplying offal and dead livestock to the renderers understand their obligations under the rule.

A copy of the final guidance can be found at http://www.fda.gov/cvm/Guidance/guide195.pdf .