The collaboration combines Native Microbials' microbial discovery and development platform with Zesty Paws' distribution network. The companies said they will work exclusively on select canine product formulations developed through the partnership, which will be commercialized through Zesty Paws' U.S. distribution network.
"We're thrilled to partner with Zesty Paws to deliver first-of-its-kind microbial solutions that directly target GI health in dogs," said Michael Seely, co-founder and CEO of Native Microbials. "This is a great example of how science-driven partnerships can deliver much needed innovation to market. We've only scratched the surface of what's possible with our microbial genomics platform, which can unlock entirely new classes of solutions for pets across a range of health needs. We look forward to expanding our partnership with Zesty Paws and bringing critical innovation to the companion animal health industry."
The products feature microbial strains discovered through Native Microbials' genomics platform. In dogs with GI dysbiosis, the strains support bile acid metabolism, produce short-chain fatty acids and rebalance microbial communities that influence digestion and immune health. Native Microbials has mapped the canine microbiome to identify beneficial microbes and deliver them in a stable, standardized form.
"At Zesty Paws, our mission has always been to elevate pet wellness through science-backed innovation and trusted quality," said Akash Bedi, CEO for North America, Middle East and India at H&H Group. "This partnership with Native Microbials marks an exciting step forward — pioneering a new era of probiotics derived directly from healthy canine guts to better support balance and vitality in pets. By combining Zesty Paws' deep understanding of pet parents' needs with Native's breakthrough microbial science, we're shaping the future of pet wellness — one where every supplement not only supports, but truly transforms, a pet's quality of life."
The collaboration will debut with two products. The first is a daily maintenance supplement that supports dogs with occasional diarrhea when administered at defined doses. The second product delivers a higher concentration of Native Microbials' microbial strains for dogs experiencing more significant GI challenges and will be available in veterinary clinics. The products are set to debut in the first half of 2026.
